Translational medicine
Our scientists are using translational medicine to guide decision-making in the drug development process.
What is translational medicine?
Translational medicine is a research discipline connecting basic science discoveries from the laboratory with the clinic and back again. It aims to use scientific insights and learnings to drive the development of patient-centered solutions and help promising treatments reach patients.
Collaborating for the future
Our multidisciplinary team of scientists are conducting cutting-edge clinical investigations within translational medicine. By leveraging state-of-the-art capabilities, including biomarker development, quantitative modeling and advanced imaging techniques, their work guides important decisions in the drug development process and drives promising candidates through our pipeline.
Translational medicine across the drug development process
Preclinical
We help drive drug development using innovative techniques to understand diseases and lay the foundation for preclinical candidates in clinical trials.
Early stage
We translate preclinical observations into clinical impact through innovative investigations to inform dosing strategies, assess target engagement and provide a robust foundation for clinical trials.
Late stage
We guide clinical decision-making leveraging biologically and clinically relevant information such as biomarker insights and sophisticated modeling, and we contribute to comprehensive labeling and drive clinical trial execution.
Deep cross-disciplinary scientific expertise
By combining diverse strengths, the team plays a unique role in translating medicines from discovery through clinical development and beyond.
Collaborating to design and execute complex early-stage clinical trials, our clinical development and operations team applies deep scientific and clinical expertise to generate high-quality data, manage regulatory logistics and support informed decision-making and regulatory approval.
Leveraging quantitative modeling to enhance portfolio decisions across the pipeline, our quantitative pharmacology and pharmacometrics team predicts therapeutic responses to optimize dosing regimens, streamline drug development strategies and create insights from internal and published competitor knowledge.
Enabling more efficient, patient-focused drug development, our digital clinical measures team leverages sensor-based digital technologies to compliantly collect objective measures of patient health and safety.
Helping to make more informed decisions in clinical trials, our translational molecular biomarkers team establishes and implements advanced molecular tests to better understand how biological processes and therapeutic interventions work.
Applying precision in biomarker and diagnostic execution, our biomarker operations team implements and executes clinical trial biomarkers and diagnostics, ensuring compliance with quality standards.
Using novel and advanced non-invasive imaging techniques, the translational imaging team enables the interrogation and sampling of biological processes and modes of therapeutic intervention that might otherwise be inaccessible, providing critical insights in preclinical and clinical settings.
Careers at Merck
If you’re interested in spearheading the discovery and implementation of novel scientific advancements and methodologies to improve patient outcomes, join our team today.
