Alzheimer’s disease is a progressive brain disorder and the most common cause of dementia, in which people lose memory, thinking skills and the ability to live independently. Alzheimer’s disease affects approximately seven million people in the U.S., with this number estimated to grow to 14 million by 2060. Recent progress in the area of human genetics in addition to advanced technology and screening tools is helping us better understand pathology in the brain and fueling innovative research in Alzheimer’s.

Nearly every day, 50 million people in the U.S. have pain, which inflicts functional, physical and psychological damage as their ability to work and maintain a family and social life is often compromised. Pain is characterized as acute or chronic. Acute pain is very common and typically the result of injury or surgery. Chronic pain persists beyond the time when tissue normally heals — typically more than three months.  We’re researching and evaluating validated targets with the aim of discovering new options for people living with both acute and chronic pain.

More than 50 million Americans are significantly impacted by conditions such as insomnia and narcolepsy as a result of the body’s inability to regulate sleep patterns. We’re conducting research to advance innovation and find solutions for people living with these disorders.

Nearly one million people in the U.S. are living with Parkinson’s disease. The progressive nervous system disorder is characterized by tremors, slow movements, loss of facial expression, impaired cognition and loss of ability to function independently. Given the impact of Parkinson’s, our research is focused on the potential to slow or halt disease progression.3

Neuromuscular diseases are a group of conditions that affect the nerves and muscles in millions of people worldwide which often have limited treatment options, leading to progressive weakness, loss of mobility and impaired function.